Program mission, vision, and goals Mission statement The mission of the Mass General Brigham MLS training program is to provide high-quality theoretical and clinical education to prepare future medical laboratory scientists with the skills, knowledge, and values required of the profession. Training will emphasize professional and ethical behavior needed to function in the clinical laboratory and to become a vital member of a health care team. Vision statement The vision of the Mass General Brigham MLS training program is to sustain a well-trained competent workforce dedicated to excellence in the practice of laboratory medicine and committed to patient care. Program goals The education goals of the MLS Program reflect Mass General Brigham’s commitment to education by training, teaching, and educating the next generation of laboratory professionals. The goals of the MGB MLS Program are as follows: Provide high-quality instruction in all major laboratory disciplines relevant to the practice of medical laboratory science Prepare students with the technical skills and theoretical knowledge necessary to function competently in the field of medical laboratory science Provide an educational environment that fosters curiosity, critical thinking, and academic growth Develop foundational knowledge of laboratory-related quality control, and foster an appreciation for quality assurance and improvement initiatives impacting daily laboratory operations Promote ethical behavior as a foundation for leadership and education Encourage professional curiosity and instill the value of continuing education for growth and maintenance of professional competence Prepare students to contribute to an interprofessional healthcare team by working collaboratively with other healthcare professionals to improve patient safety and provide patient-centered care Provide an atmosphere that promotes polite and professional communication between colleagues, patients, and all members of the healthcare team Prepare graduates to task-switch effectively to meet the demands of typical workforce conditions and provide simulated and real-world experiences that enhance their ability to work under pressure safely and effectively Prepare medical laboratory science graduates for entry-level positions in the workforce Provide our community with highly skilled, competent, professional, and ethical medical laboratory scientists Accreditation statement The MGB MLS Program is seeking accreditation through the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS). The Mass General Brigham Medical Laboratory Science Program is recognized as a Serious Applicant for Initial Accreditation. NAACLS 5600 N. River Rd., Suite 720 Rosemont, IL 60018-5119 Phone: (773) 714-8880 Email: NAACLS@naacls.org
Dr. Gimferrer's Pearl looks at Human Leukocyte Antigen Testing, and the important role it plays in maintaining immune system homeostasis after organ transplantation.
In this episode of “Lab Medicine Rounds,” guest host Ann Moyer, M.D., Ph.D., speaks with Justin Kreuter, M.D., transfusion medicine pathologist and assistant professor of pathology and laboratory medicine at Mayo Clinic, about common misunderstandings and practical ways to teach the basics of...
Original article published in the current issue of The Lancet Infectious Diseases by Brendish et al. Authors aimed to evaluate the impact of syndromic…
10 August 2023 – While there has been progress in building laboratory capacity in the Eastern Mediterranean Region, significant challenges remain, such as a lack of national policy and strategic planning for laboratory services, insufficient funding, insufficiently trained laboratory staff,...
L'histoire de Theranos et de sa fondatrice Elizabeth Holmes.
🔎 Découvrez l'histoire fascinante et complexe de Theranos et de sa fondatrice, Elizabeth Holmes, dans notre nouvelle vidéo. Nous décomposons l'ascension fulgurante de cette startup de biotechnologie jusqu'à sa chute spectaculaire. Nous explorons les allégations de fraude, les promesses rompues et le rôle controversé d'Elizabeth Holmes. Plongez avec nous dans cette leçon mémorable sur l'éthique en entreprise et l'innovation. N'oubliez pas de liker, partager et commenter si vous appréciez notre contenu ! #Theranos #ElizabethHolmes #ScandaleSiliconValley #Biotechnologie #Entrepreneuriat #Fraude #ÉthiqueEntrepreneuriale
« Entrepreneurs déchus, que sont-ils devenus ? », épisode 2/6Tout au long de l’été, Usbek & Rica revient sur la chute et la reconversion de ces dirigeants d’entreprise autrefois au sommet de leur gloire. Troisième volet avec Elizabeth Holmes, fondatrice de l’entreprise de biotech Theranos promettant de révolutionner la prise de sang… sauf que non, et que cela a mi en péril la vie de malades en plus de quelques milliards de dollars.
Should you Assess Rheumatoid Factor Serially? Save Dr. Jack Cush discusses abstract OP0272 at EULAR 2023 in Milan, Italy. ADD THE FIRST COMMENT If you are a health practitioner, you may Login/Register to comment.Due to the nature of these comment forums, only health practitioners are allowed to...
Viome vs. Thorne: Which Is The Best At-Home Microbiome Test? An RN compares Viome and Thorne at-home gut tests, with details on cost, tests offered, and more.
An emerging technology (ET) for laboratory medicine can be defined as an analytical method (including biomarkers ) or device ( software, applications, and algorithms) that by its stage of development, translation into broad routine clinical practice, or geographical adoption and implementation has the potential to add value to clinical diagnostics. Considering the laboratory medicine-specific definition, this document examines eight key tools, encompassing clinical, analytical, operational, and financial aspects, used throughout the life cycle of ET implementation. The tools provide a systematic approach starting with identifying the unmet need or identifying opportunities for improvement (Tool 1), forecasting (Tool 2), technology readiness assessment (Tool 3), health technology assessment (Tool 4), organizational impact map (Tool 5), change management (Tool 6), total pathway to method evaluation checklist (Tool 7), and green procurement (Tool 8). Whilst there are differences in clinical priorities between different settings, the use of this set of tools will help support the overall quality and sustainability of the emerging technology implementation.
Interpretation of laboratory data is a comparative procedure and requires reliable reference data, which are mostly derived from population data but used for individuals in conventional laboratory medicine.
Sepsis, defined by the Society of Critical Care Medicine (SCCM) Sepsis-3 criteria, is life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis and septic shock are high causes of mortality worldwide, resulting in the death of 1 in 3 to 1 in 6 patients in whom...
Testing for abnormal immunoglobulins was based previously on serum electrophoresis and immunofixation only.In the last years, however, free light chain (FLC) testing in serum became one imp...
Navigating long-term care options? The experts at European Financial Review delve into the crucial support role of long-term care consultants. From financial planning to personalized solutions, understand how these professionals assist in making informed choices for you and your loved ones'...
Gilbert C FAURE's insight:
Medical Laboratory Scientists
An equally crucial role in the healthcare sector is that of medical laboratory scientists. Many patients may not interact directly with these professionals, yet their impact on patient care cannot be underestimated. The importance of diagnostic tests in the medical field goes without saying, and medical laboratory scientists are chiefly in charge of these tests.
Several institutions offer bachelor medical laboratory science programs, which equip students with the necessary skills and knowledge they need to excel in this field. However, this demanding role requires technical prowess, excellent analytical and problem-solving skills, and a deep commitment to patient health and safety.
Medical laboratory scientists analyze various body fluids and tissues, helping to diagnose, treat, and prevent diseases. They use sophisticated laboratory equipment and apply their vast knowledge in biology, chemistry, and medicine to ensure the accuracy and precision of these tests. Their role is integral in the medical disease management process, as they provide doctors with critical information that guides them in deciding the most appropriate treatment path for the patients.
Yeon Ju Seo, M.D., Inseong Oh, M.D., Minjeong Nam, M.D., Ph.D., Sue Shin, M.D., Ph.D., Eun Youn Roh, M.D., Ph.D., and Eun Young Song, M.D., Ph.D.. Ann Lab Med 2023;43:596-604.https://doi.org/10.3343/alm.2023.43.6.596...
A new review of literature on #COVID19-sniffing canines shows #dogs outperformed or matched reverse-transcription polymerase chain reaction (#RTPCR) tests or…
Multiplex immunohistochemistry, to identify co-localized proteins, runs into problems with secondary antibodies. A system that instead directly labels primary antibodies can allow faster and more complicated assays.
The 2023 AACC Annual Scientific Meeting & Clinical Lab Expo is a world-renowned exposition for clinical laboratory products and services that brings together the global laboratory medicine community.
Cyrex Laboratory Advanced Immunity Testing At Westcoast Integrative Health we take risk assessment and the treatment of chronic diseases very seriously, which is why Cyrex Laboratory testing is a critical part of our functional diagnostic process in some cases. Dr Davies has been following Cyrex Laboratories work for many years through continuing education but prior to last year (2017) their testing was not available in Canada. Cyrex Laboratory tests are broken down into different arrays, which are relevant to different health conditions. The different arrays are very unique in what they test and are not offered by other laboratories, which makes Cyrex testing essential to access for certain medical conditions. Cyrex testing was mostly developed by a brilliant PhD in Immunology named Dr Aristo Vojdani. Dr Vojdani is a pillar in the functional medicine movement developing testing like the Cyrex Arrays, but also doing primary research in autoimmunity and educating medical professionals about the actual causes of immune associated conditions. The current conventional medicine model for the treatment of autoimmunity is focused on immune suppression or the use of biological agents like Humira™. Humira is a biological drug that blocks the effects of a specific inflammatory molecule in our bodies. Immune suppressive drugs like prednisone or non-steriodal anti-inflammatory medications are also typically used along with chemical therapy treatments like methotrexate or DMARDS like plaquenil. None of these treatments are necessarily bad on a short-term basis, but should really not be used long-term. The same general approach is used for neurological conditions like Parkinson’s Disease, Multiple Sclerosis, and Alzheimer’s Disease. The disappointing thing is that the treatments for these conditions are not even close to as targeted as what treatments are now available for autoimmune diseases. Treatments for PD, MS and Alzheimer’s currently only try to control symptoms and do not manipulate the progression of disease or reverse the damage that is occurring in these conditions, with the exception of MS, which has target medications that are known to not be that effective. Functional medicine does not necessarily exclude the short-term use of these medications to keep a person safe from the effects of their own immune system or to manage symptoms. What functional medicine does, in parallel to these treatments, is find the mechanistic causes of the autoimmune or neurological disease, eliminate the proposed triggers, including foods, environmental agents, and chronic infections in our bodies. A functional medicine approach may be used in parallel with conventional medicine. I have personally collaborated with rheumatologists, gastroenterologists, internists, pediatricians and oncologists in the treatment of multiple chronic health conditions with a focus on what I do and not initially altering the treatment of conventional medicine. This is why there is really nothing to loss, using a knowledgable functional medicine doctor, along with the conventional medical model. Once we can identify and reduce/eliminate some of the cross-reactive triggers then we manipulate the immune system to stop damaging the body. This often occurs naturally, but occasionally requires the use of immune modulating treatments like vitamin D regulators, CBD, Low Dose Naltrexone, certain plant compounds and very specific probiotics. As mentioned, for autoimmune conditions, all of this may be done along side conventional treatment, if that is what a person prefers, or may be offered as an alternative to conventional treatment for cases that are medically under control and in patients that are safe. For neurological conditions such as MS, PD and Alzheimer’s Disease functional medicine is critical as the treatments offered are not slowing the progression of disease at all. Don’t take my word for it! Further reading may include the works of Dr Mark Hyman, Dr Amy Myers, and Dr Tom O’Bryans. A complete cure is out there! Critical testing to consider for simple prevention or for the initial assessment of chronic disease is the Array 2 – Intestinal Antigenic Permeability Screen and the Array 12 – Pathogen Associated Immune Reactivity Screen The following is an overview of Cyrex Arrays and what each of these unique tests assess. Predictive Antibody Testing – Array 5 | Array 6 | Array 7 | Array 7X | Array 8 Assessments your healthcare professional can use to identify autoimmune reactivity at its early stages. Array 5 – Multiple Autoimmune Reactivity Screen™ Measures Predictive Antibodies, some of which can appear up to ten years before any clinical symptoms. Array 5 efficiently and economically assesses possible tissue damage to multiple organs of the body. Parietal Cell + ATPase IgG + IgA Combined Intrinsic Factor IgG + IgA Combined ASCA + ANCA IgG + IgA Combined Tropomyosin IgG + IgA Combined Thyroglobulin IgG + IgA Combined Thyroid Peroxidase (TPO) IgG + IgA Combined 21 Hydroxylase (Adrenal Cortex) IgG + IgA Combined Myocardial Peptide IgG + IgA Combined Alpha-Myosin IgG + IgA Combined Phospholipid IgG + IgA Combined Phospholipid IgG + IgA Combined Platelet Glycoprotein IgG + IgA Combined Ovary/Testis* IgG + IgA Combine Fibulin IgG + IgA Combined Collagen Complex IgG + IgA Combined Arthritic Peptide IgG + IgA Combined Osteocyte IgG + IgA Combined Cytochrome P450 (Hepatocyte) IgG + IgA Combined Insulin + Islet Cell Antigen IgG + IgA Combined Glutamic Acid Decarboxylase 65 (GAD 65) IgG + IgA Combined Myelin Basic Protein IgG + IgA Combined Asialoganglioside IgG + IgA Combined Alpha + Beta Tubulin IgG + IgA Combined Cerebellar IgG + IgA Combined Synapsin IgG + IgA Combined Array 6 – Diabetes Autoimmune Reactivity Screen™ Assesses markers of the autoimmune components of diabetes. Array 6 can be used as a tool to identify reactivity prior to the onset of diabetes, and to monitor a patient who is already diagnosed with diabetes to see how well treatment protocols are working. Glutamic Acid Decarboxylase 65 (GAD 65) IgG + IgA Combined Insulin + Islet Cell Antigen IgG + IgA Combined Array 7 – Neurological Autoimmune Reactivity Screen™ Array 7 assists in the early detection of neuro-autoimmunity, evaluates severity of the autoimmune response, and assists in monitoring the effectiveness of related treatment protocols. Myelin Basic Protein IgG + IgA Combined Asialoganglioside IgG + IgA Combined Alpha + Beta Tubulin IgG + IgA Combined Cerebellar IgG + IgA Combined Synapsin IgG + IgA Combined Array 7X – Neurological Autoimmune Reactivity Screen™ – Expanded Array 7X helps in early detection of neuro-autoimmune reactivity in early detection of autoimmune reactivity of peripheral and central nervous system, and assists in monitoring the effectiveness of related treatment protocols. Myelin Basic Protein IgG + IgA Combined Myelin Basic Protein IgM Asialoganglioside IgG + IgA Combined Asialoganglioside IgM Alpha + Beta Tubulin IgG + IgA Combined Alpha + Beta Tubulin IgM Cerebellar IgG + IgA Combined Cerebellar IgM Synapsin IgG + IgA Combined Synapsin IgM Array 8 – Joint Autoimmune Reactivity Screen™ Array 8 assists in the early detection of connective tissue disorders, and in monitoring the effectiveness of related treatment protocols. Arthritic Peptide IgG + IgA Combined Collagen Complex IgG + IgA Combined Fibulin IgG + IgA Combined Barrier Permeability Assessments – Array 2 | Array 20 | Array 22 When there is a breach in essential defense barriers, the body is at risk for developing environmentally-induced autoimmunity. Array 2 – Intestinal Antigenic Permeability Screen™ Array 2 measures intestinal permeability to large molecules, which inflame the immune system. Actomyosin IgA Occludin/Zonulin IgG Occludin/Zonulin IgA Occludin/Zonulin IgM Lipopolysaccharides (LPS) IgG Lipopolysaccharides (LPS) IgA Lipopolysaccharides (LPS) IgM Array 20 – Blood-Brain Barrier Permeability™ Array 20 assists in the assessment of increased risk of neurogenerative disorders, including but not limited to Multiple Sclerosis, Lou Gehrig’s Disease, Senile Dementia, Alzheimer’s Disease, Parkinson’s Disease, Epilepsy and Stroke. Helps in the early investigation of contact sports-related Traumatic Brain Injury, and evaluates the breach of Blood-Brain Barrier caused by stress, trauma or environmental triggers, even in the absence of apparent concussion or brain injury. Blood Brain Barrier Protein IgG + IgA combined Blood Brain Barrier Protein IgM Array 22 – Irritable Bowel / SIBO Screen™ Array 22 provides a more accurate test for Irritable Bowels and SIBO by assessing IgG, IgA and IgM antibodies to Bacterial Cytotoxins and Cytoskeletal Proteins. With Array 22 one can identify a trigger of irritable bowels and the specific intestinal barrier damage they cause. It improves upon the standard breath test for SIBO by eliminating the need for exhaustive dietary restriction and collection protocols for patients, while providing better specificity and sensitivity through serum antibody testing. Bacterial Cytotoxins IgG Bacterial Cytotoxins IgM Cytoskeletal Proteins IgA Bacterial Cytotoxins IgA Cytoskeletal Proteins IgG Cytoskeletal Proteins IgM Reactivity Trigger Assessments – Array 3 | Array 4 | Array 10 | Arrays 10-90 & 10-90X | Arrays 10C & 10-90P | Array 11 | Array 12 Environmental triggers of autoimmunity include dietary proteins, chemicals and heavy metals and latent pathogens. Array 3 – Wheat/Gluten Proteome Reactivity and Autoimmunity™ Array 3 accurately identifies Gluten Reactivity, and measures antibody production against 8 wheat proteins and peptides, 3 essential structure enzymes and the Gliadin-Transglutaminase Complex. Array 4 – Gluten-Associated Cross-Reactive Foods and Food Sensitivity™ Array 4 identifies reactivity to foods known to cross-react to gluten and reactivity to newly introduced foods on a gluten free diet to which you are sensitized. Array 10™ – Multiple Food Immune Reactivity Screen™ This unique, revolutionary panel measures reactivity to 180 food antigens in the cooked, raw, modified or processed form on the same panel. Array 10 assists in early detection of dietary-related triggers of autoimmune reactivity and monitors the effectiveness of customized dietary protocols. Array 10-90™ – Multiple Food Immune Reactivity Screen™ Array 10-90X – Add-on Panel These Arrays are designed to give you the same unique, revolutionary features you get from Array 10 with two options that allow flexibility. Both the Array 10-90 and 10-90X assist in early detection of dietary-related triggers of autoimmune reactivity and monitor the effectiveness of customized dietary protocols. Array 11 – Chemical Immune Reactivity Screen™ Array 11 identifies the loss of immune intolerance associated with toxic chemicals exposure, which may lead to autoimmune reactivity. It assists in setting guidelines for the avoidance of specific chemicals to reduce the risk of igniting the autoimmune process, and monitoring the effectiveness of the clinical management of protocols. Aflatoxins IgG + IgA Combined Aflatoxins IgM Formaldehyde + Glutaraldehyde IgG + IgA Combined Formaldehyde + Glutaraldehyde IgM Isocyanate IgG + IgA Combined Isocyanate IgM Trimellitic + Phthalic Anhydrides IgG + IgA Combined Trimellitic + Phthalic Anhydrides IgM Benzene Ring Compounds IgG + IgA Combined Benzene Ring Compounds IgM BPA Binding Protein IgG + IgA Combined BPA Binding Protein IgM Bisphenol A IgG + IgA Combined Bisphenol A IgM Tetrabromobisphenol A IgG + IgA Combined Tetrabromobisphenol A IgM Tetrachloroethylene IgG + IgA Combined Tetrachloroethylene IgM Parabens IgG + IgA Combined Parabens IgM Mercury Compounds IgG + IgA Combined Mercury Compounds IgM Mixed Heavy Metals (Nickel, Cobalt, Cadmium, Lead, Arsenic) IgG + IgA Combined Mixed Heavy Metals (Nickel, Cobalt, Cadmium, Lead, Arsenic) IgM Array 12 – Pathogen Associated Immune Reactivity Screen™ Array 12 – (PAIRS), assesses immune response to 29 viral, bacterial, fungal, parasitic and stealth organism antigens that may be latent in the body. Understanding which dormant pathogens are triggers of cross-reactivity, immune reactivity, and potential autoimmune reactivity is crucial for better addressing patient needs. Porphyromonas gingivalis Heliobacter pylori Yersinia enterocolitica Candida albicans Entamoeba histolytica Cryptosporidium Human HSP-60/Chlamydia HSP-60 Streptozymes Mycoplasmas Klebsiella Aspergillus Stachybotrys chartarum Hepatitis C virus Human Herpesvirus-6 Babesia+Erhlichia+Bartonella Streptococcus mutans Campylobacter jejuni Clostridium dificile Rotavirus Giardia lamblia Blastocystis hominis Chlamydias Streptococcal M protein Acinetobacter Mycobacterium avium Penicillum Citrullinated EBV Cytomegalovirus Borrelia burgdorferi Mucosal Immune System Assessment Array 14 – Mucosal Immune Reactivity Screen™ The mucosal membrane acts as a first line of defense before Predictive Antibodies, Barrier Permeability and Reactivity Triggers can influence autoimmune reactivity. The Array 14 Mucosal Immune Reactivity Screen™ is a uniquely designed salivary assessment which measures antibodies to both SIgA and SIgM. The test assesses mucosal immune reactivity to: Markers of barrier integrity Immune reactions against environmental triggers Autoimmune reactivity Lipopolysaccharides Actomyosin Calprotectin Gamma-Gliadin Gluteomorphin Transglutaminase-2 Soy Alpha + Beta Casein Aflatoxin Mercury Rotavirus Blood-Brain Barrier Protein Occludin/Zonulin ASCA/ANCA Alpha-Gliadin Glutenin Wheat Germ Agglutinin Egg Corn Casomorphin Bisphenol-A Mixed Heavy Metals Myelin Basic Protein Immune Complex
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