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Tregs Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via CTLA-4 #OA @ImmunityCP http://t.co/m8NfHU4dT3
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Scooped by Gilbert C FAURE |
Scoop.it!
Gilbert C FAURE's insight:
Highlights•Short-term Treg cell depletion enhances primary and secondary antibody production•Depletion of Treg cells can either enhance or inhibit antigen-specific Tfh cell formation•Deletion or blockade of Treg cell CTLA-4 enhances Tfh cell formation, IL-4 production, and IgE•Tfr cells possess similar in vitro suppressive CTLA-4 function to Treg cells
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