Defusing inflammasomes | Immunology | Scoop.it
From jem.rupress.org - February 16, 2018 1:05 PM
In this issue of JEM, Boucher et al. (<https://doi.org/10.1084/jem.20172222>;) report isolation of active caspase-1 from macrophages after inflammasome activation. Surprisingly, they find that caspase-1 is quickly inactivated upon autoproteolytic processing.