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Defusing inflammasomes

Defusing inflammasomes | Immunology | Scoop.it
In this issue of JEM, Boucher et al. (<https://doi.org/10.1084/jem.20172222>;) report isolation of active caspase-1 from macrophages after inflammasome activation. Surprisingly, they find that caspase-1 is quickly inactivated upon autoproteolytic processing.
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Free Access for February 2018

Free Access for February 2018 | Immunology | Scoop.it
Year in Review 2017
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Immunometabolism in 2017: Driving immunity: all roads lead to metabolism In 2017, studies of cellular metabolism broadly permeated immunological… show more Edward J. Pearce & Erika L. Pearce Nature Reviews Immunology | Year in Review Neuroimmunology in 2017: The central nervous system: privileged by immune connections Over the past few years, interest in the field of neuroimmunology has… show more Jonathan Kipnis & Anthony J. Filiano Nature Reviews Immunology | Year in Review Macrophages and monocytes in 2017: Macrophages and monocytes: of tortoises and hares Monocytes and tissue macrophages represent two main branches of the… show more Steffen Jung Nature Reviews Immunology | Year in Review Cancer immunotherapy in 2017: The breakthrough of the microbiota In 2017, epidemiological studies in humans and experiments in mouse models… show more Guido Kroemer & Laurence Zitvogel Nature Reviews Immunology | Year in Review Vaccines in 2017: Closing in on a Zika virus vaccine
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